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EC number: 247-279-7 | CAS number: 25811-35-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effect on aquatic microorganisms up to the limit of water solubility. Read across
Key value for chemical safety assessment
Additional information
Data on the toxicity of
2,2-bis[[(1-oxoheptyl)oxy]methyl]propane-1,3-diyl bisheptanoate (CAS
25811-35-2) to aquatic microorganisms are not available. In accordance
to Regulation (EC) No 1907/2006 Annex XI, 1.5 a read across to the
structurally related substances decanoic acid, mixed esters with
heptanoic acid, octanoic acid, pentaerythritol and valeric acid (CAS No.
71010-76-9) and Fatty acids, C7, C8, C10 and 2-ethylhexanoic acid,
tetraesters with pentaerythritol (CAS 68424-31-7) was conducted. This
read-across is justified in detail in the overall summary (IUCLID
section 6.2) and within the analogue justification in IUCLID Section 13.
One study investigating the toxicity of decanoic acid, mixed esters with
heptanoic acid, octanoic acid, pentaerythritol and valeric acid (CAS No.
71010-76-9) to aquatic microorganisms is available (Dickinson, 2008).
The GLP study was conducted under static conditions according to OECD
209 using non-adapted activated sludge obtained from a domestic sewage
treatment plant as inoculum. Test concentrations of 10, 100 and 1000
mg/L were prepared. Test substance was added directly to the test
vessels. The test substance did not inhibit the respiration rate of
activated sludge microorganisms at any of the concentrations employed in
the test. Hence, the 3 h-EC50 was determined to be > 1000 mg/L based on
the nominal test concentration. Therefore it can be concluded that the
test substance will not exhibit effects on the respiration rate of
microorganisms.
The toxicity of Fatty acids, C7, C8, C10 and 2-ethylhexanoic acid,
tetraesters with pentaerythritol (CAS 68424-31-7) to aquatic
microorganisms was tested in a cell multiplication inhibition test
according to Bringman and Kuehn (1980) (Comber and Coleman, 1991). No
inhibition on the growth of Pseudomonas putida was observed at the
tested concentration (10 mg/L nominal). Therefore an EC10 and EC50 (6h)
> 10 mg/L (nominal) was determined. Based on the available results from
two structurally related read-across substances (in accordance to
Regulation (EC) No 1907/2006 Annex XI, 1.5) which are characterized by a
similar ecotoxicological profile and comparable structure, it can be
concluded that 2,2-bis[[(1-oxoheptyl)oxy]methyl]propane-1,3-diyl
bisheptanoate (CAS 25811-35-2) will not exhibit short-term effects on
aquatic microorganisms up to the limit of water solubility.
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