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Hydrolysis

The hydrolysis of the test item (1,6-hexanediyl-bis(2-[2-{1-ethylpentyl}-3-oxazolidinyl]ethyl) carbamate) was investigated using HPLC-MS and GC-MS. Measurements revealed a fast hydrolysis of the test item. The hydrolysis degradation products of the test item were identified qualitatively. The first hydrolysis product was determined to be 2-ethylhexanal. The second hydrolysis degradation product was identified on the basis of its molecular weight. The second, more likely hydrolysis product, which is in good consistency with the experimentally determined molecular weight, is 1,6 hexanediyl-bis-carbamic acid bis(N-hydroxyethyl-2-aminoethyl) ester.

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