Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

For both 6-(isononanoylamino)hexanoic acid, compound with 2,2’,2’’-nitrilotriethanol and 6-(isononanoylamino)hexanoic acid, reliable tests demonstrate ready biodegradability. The 10 day-window was fulfilled in the respective tests.

Additional tests on inherent biodegradability support these results. 6-(isononanoylamino)hexanoic acid, compound with 2,2’,2’’-nitrilotriethanol (97% within 11 days, RL1) and 6-(isononanoylamino)hexanoic acid (93% within 17 days; RL1) proved to be inherently biodegradable in Zahn-Wellens-tests (OECD 302 B).

A further study on the mode of actual degradation (IUCLID section 5.2.4) is available for 6-(isononanoylamino)hexanoic acid: transformation intermediates were analytically determined in a Zahn-Wellens-tests (OECD 302 B; RL2). The major metabolite determined after 7 days was isononanoic acid (approximately 60 mg/L), which was however fully metabolized after 14 days. The other expected metabolites were found only in low concentrations (at maximum 5 mg/L) after 7 as well as 14 days. Elimination due to adsorption was accounted for (determined however to be negligible).

6-(isononanoylamino)hexanoic acid, compound with 2,2’,2’’-nitrilotriethanol - and by read across also the very similar 6-(isononanoylamino)hexanoic acid - may be regarded as inherently biodegradable in the marine environment. This can be deduced from a test on aerobic biodegradability in seawater according to OECD 306 (reliability category 2).