Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-456-7 | CAS number: 1333490-26-8
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 15 July 2009-4 August 2009
- Reliability:
- 3 (not reliable)
Data source
Materials and methods
- Principles of method if other than guideline:
- Crystals of 3508 were imaged using polarized light on the Zeiss Axio Optical Microscope at 100x magnification.
Four crystals were chosen and measurements were taken using Image-Pro Plus 6.0. - GLP compliance:
- not specified
- Type of distribution:
- other: Photomicroscopy
Test material
- Reference substance name:
- (2E)-2-cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-({4-methoxy-3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}amino)prop-2-enamide; propan-2-ol
- EC Number:
- 700-456-7
- Cas Number:
- 1333490-26-8
- Molecular formula:
- C26H31Cl2N5O4 · 1/2(C3H8O1)
- IUPAC Name:
- (2E)-2-cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-({4-methoxy-3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}amino)prop-2-enamide; propan-2-ol
- Details on test material:
- Molecular weight: 548.47
Batch: 09-002
Purity: >92% (Contains 6.5% isopropanol as a hemi-solvate
Appearance: Yellowish solid
Constituent 1
Results and discussion
Particle size
- Percentile:
- D50
- Remarks on result:
- other: Result= Aspect Ratio: 3.0(migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.)
Any other information on results incl. tables
Sample Length (um) Width (um) Aspect Ratio
Crystal1 75.2 22.3 3.37
Crystal2 40.6 13.5 3.01
Crystal3 94.9 34.8 2.73
Crystal4 62.9 22.7 2.77
Avg. 2.97
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
