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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Version / remarks:
1992
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Partition coefficient:
< -3
Temp.:
21 °C
Remarks on result:
other: pH not reported in SNIF
Conclusions:
The log Pow of the test item was determined to be below -3 at 21 °C.
Executive summary:

A study was conducted according to Regulation 92/69/EWG, method A.8 to determine the octanol-water partition coefficient using the shake flask method. The log Pow of the test item was determined to be below -3 at 21 °C.

Description of key information

The log Pow of the test item was determined to be below -3 at 21 °C (reference 4.7-1).

Key value for chemical safety assessment

Additional information

A study was conducted according to Regulation 92/69/EWG, method A.8 to determine the octanol-water partition coefficient using the shake flask method. The log Pow of the test item was determined to be below -3 at 21 °C.