Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

fish early-life stage toxicity
or any other long-term toxicity test with fish
Data waiving:
other justification
Justification for data waiving:

Description of key information

At present, no study is available that can be considered as a key study or can cover the endpoint in any other way (e.g., several studies in a weight of evidence approach). The outcome of the CSA indicates that at this point in time there is no need for further testing for this endpoint.

Key value for chemical safety assessment

Additional information

Only one study was identified as containing relevant and reliable information on this endpoint (Bogers, 1995). In this study, carp (Cyprinus carpio) were exposed for 21 days to LaCl3, yielding a 21-d NOEC (based on mortality) of 0.26 mg La/L and a 21-d LC50 of > 5 mg La/L, based on geometric means of measured dissolved La concentrations. This study was however performed according to OECD guideline 204 (Fish, Prolonged toxicity test), which is insufficient to cover this endpoint in the absence of real long-term studies. The study lasted one week longer than recommended by the guideline (i.e., 21 instead of 14 days), however, since only mortality was studied as endpoint, the study can only be considered as a supporting study. Further testing is however not considered necessary since the outcome of the CSA does not indicate the need for it.