Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 212-391-7 | CAS number: 813-94-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
(24 h) 1980 mg/L D. magna
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 980 mg/L
Additional information
No data on toxicity of tricalcium dicitrate 813 -94 -5 to aquatic invertebrates are available. A 24 h aquatic invertebrate study is, however, available for the parent acid of tricalcium dicitrate, citric acid 77-92 -9 with Daphnia magna in a neutralised solution. It is considered appropriate to read across the aquatic invertebrate results to tricalcium dicitrate 813 -94 -5 because under conditions relevant to ecotoxicity assessment, the tricalcium salt of citric acid is expected to be fully dissociated. Tricalcium dicitrate is not expected to contribute to the toxicity of the substance, being a ubiquitous element.
The study determines an LC50 value based on mortality of the test organism, by today's standards it is thought by the reviewer to be more accurate to refer to an EC50 value based on immobility, due to the difficulties is determining mortality of daphnids by visual inspection. Therefore a 24 h EC50 value of 1535 mg/L was determined for the effects of citric acid 77 -92 -9 on D. magna
The resulting EC50 for citric acid is 1535 mg/L, which is equivalent to 1535 * 1.29 = 1980 mg/L of tricalcium dicitrate
using(Mass of one mole of salt)/(mass of citric acid produced when salts dissociates) = 498.4 / (2 * 192.9) = 1.29.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
