Registration Dossier

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Description of key information

Key value for chemical safety assessment

Justification for classification or non-classification

Additional information

No carcinogenicity data are available for 3,7-dimethyloct-6-enenitrile.

According to REACH, additional data on carcinogenicity need to be provided if the substance has a widespread dispersive use or frequent/long-term human exposure is given and the substance is a mutagen category 3 or there is evidence for a capacity to induce hyperplasia and/or preneoplastic lesions from repeated dose studies.

Based on the available genotoxicity data,3,7-dimethyloct-6-enenitrile

was found to be non-genotoxic. Additionally, there is no evidence from repeated dose studies that the substance is able to induce hyperplasia and/or pre-neoplastic lesions.

As a consequence, there is no indication for further testing 3,7-dimethyloct-6-enenitrile

in a carcinogenicity study.