Registration Dossier
Registration Dossier
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EC number: 224-832-0 | CAS number: 4511-42-6
Endpoint summary
Administrative data
Description of key information
EC50 (fish, 96 h) = 130 - 320 mg/L
EC50 (daphnids, 48 h) = 130 - 750 mg/L
NOEC (algae, 72 h) > 533 mg/L
NOEC (microorganisms, 3 h) ≥ 88.2 mg/L
Additional information
Since LL-lactide undergoes immediate hydrolysis in contact with water, forming lactic acid, this is the moiety of interest by read-across.
The aquatic toxicity of L-lactic acid is primarily related to its effects on pH of the test solution if not buffered. Both the fish and daphnid studies were not buffered, the algae study was buffered. Hence, effects on fish and daphnids were attributed to a pH shift. Whereas effects in the algae study can be assigned to the test substance and are not confounded with pH effects due to the acidity of lactic acid.
No effects on microbial growth were observed in an activated sludge respiration inhibition test.
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