Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

EC50 (fish, 96 h) = 130 - 320 mg/L

EC50 (daphnids, 48 h) = 130 - 750 mg/L

NOEC (algae, 72 h) > 533 mg/L

NOEC (microorganisms, 3 h) ≥ 88.2 mg/L

Additional information

Since LL-lactide undergoes immediate hydrolysis in contact with water, forming lactic acid, this is the moiety of interest by read-across.

The aquatic toxicity of L-lactic acid is primarily related to its effects on pH of the test solution if not buffered. Both the fish and daphnid studies were not buffered, the algae study was buffered. Hence, effects on fish and daphnids were attributed to a pH shift. Whereas effects in the algae study can be assigned to the test substance and are not confounded with pH effects due to the acidity of lactic acid.

No effects on microbial growth were observed in an activated sludge respiration inhibition test.