Registration Dossier
Registration Dossier
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EC number: 232-136-3 | CAS number: 7787-93-1
Endpoint summary
Administrative data
Description of key information
Additional information
Reliable short-term aquatic toxicity tests results for the registered substance, CAS 7787-93-1, are only available for freshwater fish (Cyprinus carpio). A 96-hour LC50 value of >107 mg/l has been determined, or >86 mg/l when expressed in terms of the silanol hydrolysis product (3-chloropropyl)methylsilanediol.
There are no reliable data for aquatic invertebrates and algae but data are available by reading-across from two structurally analogous substances (3-chloropropyl)dimethoxymethylsilane (CAS 18171-19-2) and (3-chloropropyl)diethoxymethylsilane (CAS 13501-76-3).
A 48-hour EC50 of 295 mg/l has been determined for effects on mobility of the invertebrate Daphnia magna with (3-chloropropyl)diethoxymethylsilane (CAS 13501-76-3), or 216 mg/l when expressed in terms of the silanol hydrolysis product (3-chloropropyl)methylsilanediol (key data).
A 48-hour EC50 value of >100 has been determined for effects on mobility of the invertebrate Daphnia magna with (3-chloropropyl)dimethoxymethylsilane (CAS 18171-19-2), or >85 mg/l when expressed in terms of the silanol hydrolysis product (3-chloropropyl)methylsilanediol (supporting study).
An algal inhibition study with (3-chloropropyl)diethoxymethylsilane (CAS 13501-76-3) reports a 72-hour EC50 value of 437 mg/l and NOEC of 57 mg/l in the same study. It is likely that the test organisms were exposed to the hydrolysis products of the substances therefore the EC50 and NOEC values are 321 mg/l and 42 mg/l respectively, when expressed in terms of the silanol hydrolysis product (3-chloropropyl)methylsilanediol.
Results of invertebrate and algal tests conducted with the registered substance may have been influenced by the pH of the test media and have therefore been discounted when assessing the hazard of the substance.
A reliable activated sludge respiration inhibition test is also available for the registered substance. A 3 hour EC50 value of 400 mg/l has been determined in the test.
No long-term aquatic toxicity data are available for dichloro(3-chloropropyl)methylsilane or related substances.
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