Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-077-5 | CAS number: 78-04-6
Carcinogenicity
Administrative data
Description of key information
The following study has been submitted to address the carcinogenicity endpoint:
EFSA (2004) Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commision to assess the health risks to consumers associated with exposure to organotins in foodstuffs (Question No EFSA-Q-2003-110). The EFSA Journal 102: 1-119.
As the reference is secondary literature, it has been allocated a Klimisch score of 4.
Key value for chemical safety assessment
Justification for classification or non-classification
Additional information
According to the EFSA Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission to assess the health risks to consumers associated with exposure to organotins in foodstuffs (2004), no statistically significant increases in tumour incidences were observed inDibutyltin diacetatedosed rats or mice compared to the controls. An accidental loss of tissues from high dose female rats precluded an evaluation of the carcinogenicity of dibutyltin diacetate in female rats. However , the substance is not likely to be carcinogenic.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
