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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

In a reliable study, the 72h-EC50 on a marine unicellular algae Skeletonema costatum were found to 16.89 mg/L (nominal, growth rate), corresponding to a 72h-EC50 = 5.1 mg/L in active ingredient. The 72h-NOEC was determined to be 10.0 mg/L (nominal, growth rate), which correspond to a 72h-NOEC = 3.0 mg/L in active ingredient.
Thus, the Lauramidopropylhydroxysultaine is considered as toxic to algae.

Key value for chemical safety assessment

EC50/LC50 for marine water algae:
5.1 mg/L
EC10, LC10 or NOEC for marine water algae:
3 mg/L

Additional information

One reliable key study (Opus, 2009) has been conducted on Mackam LSB-50 in accordance with the Principles of Good Laboratory Practice Regulations.

The growth inhibition on a marine unicelluar algae (Skeletonema costatum) was determined in a 72 -hour static test according to the ISO 10253 2006 (Water quality - Marine Algal Growth Inhibition Test with Skeletonema costatum and Phaeodactylum tricornutum).

Data are missing regarding the monitoring of the substance concentration but the substance is considered as stable during the test and validity criteria are fulfilled. Therefore, this study is considered to have a reliability of (2). The following results were obtained:

- 72h-EC50 = 16.89 mg/L (nominal, test item) and thus 5.1 - 8.9 mg/L in active ingredient

-72h-NOEC = 10 mg/L (nominal, test item) and thus 3 - 5 mg/L in active ingredient

Mackam LSB-50 is considered to be harmful to the marine unicellular algae Skeletonema costatum and Lauramidopropylhydroxysultaine is considered as toxic to algae.