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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

In two studies performed on Mackam LSB-50 (commercial product, aqueous solution) according to OECD guidelines 310 and 306, the 60% pass level was reached (even if 10-day window criteria is not fulfilled in OECD 310 study). Moreover, several studies are available on an analogous substance and support this result.
Thus, using a weight of evidence approach, Lauramidopropylhydroxysultaine is considered as readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable but failing 10-day window

Additional information

Two studies were performed on Mackam LSB-50 (commercial product, aqueous solution) as the test item is manufactured and used in a liquid form.

In a reliable study conducted according to OECD 310 (reliability 1; key study) a degree of biodegradation of 62.2% was reached after 28 days. The 60% pass level was reached even if 10 day window criteria is not fulfilled. A biodegradation study was performed on seawater with Mackam LSB-50 according to OECD guideline 306 and in compliance with GLP (reliability 1; key study). The biodegradation level of the test substance was 61% within 28 days incubation in seawater and the substance is considered as readily biodegradable in seawater. Other biodegradation data are avalaible on a similar substance, which differs in alkyl chain length. The three biodegradation studies performed on Cocamidopropylhydroxysultaine support the results obtained on Lauramidopropylhydroxysultaine.

Thus, using a weight of evidence approach, Lauramidopropylhydroxysultaine is considered as readily biodegradable.