Registration Dossier

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Study period:
Start date of the experimental work: 18 June 2009 and Completion date of the experimental work: 22 June 2009.
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
static method
Key result
Temp.:
20 °C
Vapour pressure:
62 Pa
Remarks on result:
other: mean of runs 1 and 2

Full test results:

 Temp /°C Temp / K  P / mbar  ** P / Pa 
          Run 1
 *20  293.15  0.62 62 
 43.6  316.75  2 200 
 49.2  322.35  2.5 250 
 59.6  332.75  4.1 410 
 68.5  341.65  6.3 630 
 80.4  353.55  9.5 950 
 90.5  363.65  12.7 1270 
          Run 2
 *20  293.15  0.62 62 
 39.1  312.25  1.5 150 
 52.4  325.55  2.9 290 
 61.2  334.35  4.0 400 
 72.2  345.35  6.3 630 
 79.6  352.75  8.4 840 
 90.2  363.35  10.7 10701 

*: Determined by extrapolation

**: Calculated

Comment: Sample degassed over a period of 10 hours.

Result : 62 Pa at 20°C (mean of runs 1 & 2)

Conclusions:
Result : 62 Pa at 20°C (mean of runs 1 & 2)
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental starting date: 11th November 2014 and experimental completion date: 3rd November 2014.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: by loss of weight or by trapping vaporisate
Key result
Remarks on result:
other: For the test item, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation: Vapour pressure at 20 °C: 1.04 * 10-03 Pa Vapour pressure at 25 °C and 1.95 * 10-03 Pa

The vapour pressure of test substance was examined at four different temperatures. All temperatures could be evaluated as they showed reproducible weight loss. For these temperatures, 1/T was plotted against log (P).

Table: Vapour Pressures (Effusion Method)

Experiment

 T  P  Stand. Dev. P  RSD P
 No.  C  Pa  Pa  %
 2 45.0  1.96E-02 3.28E-03 16.8%
3 60.0 1.04E-01 1.14E-02 10.9%
4 75.0 3.91E-01 1.31E-02  3.4%

In this table, E-0X represents multiplication with 10-X.

 

The graph 1/T vs. log (P) shows a straight line with a correlation coefficient of - 0.9991.

 

For the test item, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:

Vapour pressure at 20 °C:          1.04* 10-03Pa

Vapour pressure at 25 °C:          1.95* 10-03Pa





Conclusions:
For the test item, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:
Vapour pressure at 20 °C: 1.04 * 10-03 Pa
Vapour pressure at 25 °C: 1.95 * 10-03 Pa
Executive summary:

The vapour presure of the test item was determined following EU A.4 using the effusion method (weight loss).

Vapour pressure was examined at four different temperatures. three temperatures could be evaluated as they showed reproducible weight loss. For these temperatures, 1/T was plotted against log (P).

Vapour pressure (Effusion method)

 Experiment Stand. Dev. P  RSD P 
 N°  °C Pa  Pa 
 2  45.0  318.2  1.96E-02  3.28E-03  16.8%
 3  60.0  333.2  1.04E-01  1.14E-02  10.9%
 4  75.0  348.2  3.91E-01  1.30E-02  3.4%

In this table, E-0X represents multiplication with 10 -x

The graph 1/T vs log (P) shows a straight line with a correlation coefficient of -0.9991.

For the test item , the following vapour pressures at 20°C and at 25°C wee calculated from the regression equation:

Vapour pressure at 20 °C: 1.04 * 10-03 Pa

Vapour pressure at 25 °C: 1.95 * 10-03 Pa

Description of key information

The study performed at Laus was used as key study and the vapour pressure were calculated from the regression equation to be 1.04*10-03 Pa at 20°C and 1.95*10 -03 Pa at 25°C

Key value for chemical safety assessment

Vapour pressure:
0.001 Pa
at the temperature of:
20 °C

Additional information