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Water solubility

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011 - 2012
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
14 g/L
Conc. based on:
test mat. (total fraction)
Incubation duration:
5 h
20 °C
Details on results:
The test item is not stable under the chosen conditions (30°C}. Therefore, conditions with shorter agitating times and conditioning times directly at 20oc were chosen.

Reduced timescale:
Approximately 2.5 g of test item and 16 ml of water were stirred at 20°C for 0.5, 1, 2, 3, 4, 5 and 24 hours. Afterwards the mixtures were conditioned without stirring at 20.0°C.

The water solubility was calculated using results from samples 1hrs to 5 hrs.

Description of key information

14 g/L at 20°C, pH 6.3

Key value for chemical safety assessment

Water solubility:
14 g/L
at the temperature of:
20 °C

Additional information

The determination was carried out by flask method according to OECD Guideline 105.

The test item is not stable with the equilibration temperature at 30°C for 24 hours therefore the solubility has been determined by the equilibration at 20°C. The solubility of 14 g/L has been calculated using the results of the samples from 1 to 5 hours.