Octadecanoic acid, reaction products with diethylenetriamine and urea, acetates

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2013

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

Identification: FAT 93580/A Lot. 0022357000
Appearance: Light yellow waxy solid

Water solubility:

< 0.1 mg/L

Temp.:

20 °C

Remarks on result:

other: pH is not mentioned

Details on results:

None

Preliminary Visual Estimation of the water solubility

Different amounts of the test item were stirred with different amounts of water at room temperature and visually checked for any undissolved particles.

Amount of test item in mg	Volume in mL	Total volume in mL	Stirring time	Appearance of mixture
988.7	50	50	30 min	undissolved
55.7	100	100	30 min	undissolved
14.1	100	100	30 min	undissolved
1.41	100	100	30 min	undissolved

According to this preliminary test the solubility of the test item in water is below 141 mg/l (without correction of the purity).

Solubility of the test item-experiment A to D:

Experiment	A	B	C	D (Blank)
Amount of test item in mg	55.7	51.2	65.7	-
Stirring time at 30°C (h)	24	48	72	72
Aliquot of the flask (mL)/End volume	10/10	10/10	10/10	10/10
Measured concentration (μg/mL)	< 0.1	< 0.1	< 0.1	-
Mean concentration (mg/L)	< 0.1	< 0.1	< 0.1	-
Solubility (mg/L)	< 0.1	< 0.1	< 0.1	-

The values of the measured concetrations of the test item in water were below lowest calibration standard of the analytical method.

Conclusions:

The water solubility of the test item at a temperature of 20 °C was determined to (without correction for the purity): <0.1 mg/l

Executive summary:

The key study was performed to determination of the water solubility of the test item according to the European Commission Regulation (EC) No.440/2008 and following OECD test guidelines 105 using the shake flask method.

Based on the findings of the study, the water solubility of the test item at a temperature of 20 °C was determined as (without correction for the purity): <0.1 mg/L

Description of key information

The water solubility of the test item at a temperature of 20 °C was determined to (without correction for the purity): < 0.1 mg/l

Key value for chemical safety assessment

Water solubility:

0.1 mg/L

at the temperature of:

20 °C