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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

Two QSAR reports were also supplied. ECOSAR was used to estimate the toxicity of 2,3-Epoxypropanol (Glycid) to Daphnia. As the lethal toxicity of epoxide chemical class for Dapnia is the worst case for this estimated value, a 48 EC50 for Daphnia 2,176.81 mg/L was determined (Brady, 2010a). 
OECD (Q)SAR (epoxides, mono neutral organic SAR (Baseline Toxicity)) was used to estimate the acute toxicity of 2,3-Epoxypropanol (Glycid) to Daphnia. The 48 EC50was estimated to be 334 mg/L (Brady, 2010b).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
334 mg/L

Additional information

Two QSAR reports have been provided to address the acute toxicity of 2,3-epoxypropanol (Glycid) to aquatic inverterates, one was generated using ECOSAR and the other using OECD QSAR Toolbox.

ECOSAR was used to estimate the toxicity of 2,3-Epoxypropanol (Glycid) to Daphnia. As the lethal toxicity of epoxide chemical class for Daphnia's the worst case for this estimated value, a 48 EC50 for Daphnia 2,176.81 mg/L was determined (Brady, 2010a).

 

OECD (Q)SAR (epoxides, mono neutral organic SAR (Baseline Toxicity)) was used to estimate the acute toxicity of 2,3-Epoxypropanol (Glycid) to Daphnia. The 48 EC50 was estimated to be 334 mg/L (Brady, 2010b).

 

Based on the prediction results described above and as the substance is readily biodegradable, the substance 2,3-Epoxypropanol (Glycid) is not classified for toxicity to the aquatic environment according to Regulation (EC) No. 1272/2008 or Directive 67/548/EEC.