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Toxicity to terrestrial arthropods

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Description of key information

The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the toxicity to terrestrial arthropods.

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Additional information

The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the toxicity to terrestrial arthropods.

Experimental data on the toxicity of 2-ethyl-2-[[(1-oxoheptyl)oxy]methyl]propane-1,3-diyl bisheptanoate (CAS 78-16-0) to terrestrial arthropods are not available. In accordance with Regulation (EC) No. 1907/2006, Annex IX, column 2, 9.4 further studies on the effects on terrestrial organisms do not have to be conducted since the chemical safety assessment indicates that there is no need.

The members of the TMP esters group are characterised by a high Koc indicating a high potential to adsorb to soil particles. Therefore the substances might be ingested by soil-dwelling organism feeding on soil particles. However, the members of the TMP esters group are in all probability not acutely toxic as indicated by the available studies on the acute toxicity of the TMP esters groupgroup members to aquatic organisms. Data on a short-term toxicity plant toxicity test according to OECD 208 available for Fatty acids, C14-18 and C16-18 unsatd., triesters with trimethylolpropane (CAS-No. 68002-79-9) indicate no toxicity (NOEC = 300 - 1000 mg/kg soil dw, LOECs = 1000 mg/kg soil dw) to plants.

A chronic exposure of terrestrial organisms is not probable since the members of the TMP esters group are readily biodegradable. Thus, they can be expected to be rapidly and ultimately degraded in the terrestrial environment. When ingested by soil dwelling organisms, the members of the TMP esters group are expected to be rapidly metabolised and thus an accumulation and/or chronic effects are not likely. Two earthworm reproduction tests according to OECD 222 are available for the TMP esters groupgroup members 2-ethyl-2-[[(1-oxoheptyl)oxy]methyl]propane-1,3-diyl bisheptanoate (CAS 78-16-0) and 2-ethyl-2-(((1-oxoisooctadecyl)oxy)methyl)-1,3-propanediyl bis (isooctadecanoate) (CAS 68541-50-4). In both studies no chronic toxicity of the substances to Eisenia fetida was determined (Eisner, 2013). The substances caused neither mortality nor a decrease in body weight of adult earthworms. Also the reproduction rates were not affected by the TMP esters group members and thus a NOECmort/repro 1000 mg/kg was reported in both studies.

In accordance with Regulation (EC) No. 1907/2006, Annex X, Column 2, 9.4 further studies on the effects on terrestrial organisms do not have to be conducted since the chemical safety assessment indicates that toxicity to terrestrial arthropds is not expected to be of concern.