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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

Reference
Name:
2-diphenylphosphinobenzoic acid
Type of composition:
legal entity composition of the substance
State / form:
solid: particulate/powder
Reference substance:
2-diphenylphosphinobenzoic acid
PBT status:
the substance is not PBT / vPvB
Justification:

2-(diphenylphosphino)benzoic acid (and the transformation product 2-(diphenylphosphino)benzoic acid oxide) are not expected to be readily or inherently biodegradable based on QSAR and publicly available data (OSPAR, 2000) for structurally analagous substances (Triphenyl phosphine; CAS: 603-35-0 and Triphenylphosphine oxide; CAS: 791 -28 -6). The substance is assessed as being potentially P i.e. meets the criteria for classification as persistent in the environment.

2-(diphenylphosphino)benzoic acid has a log Kow value of 2.9 at pH 2.0 (non-ionised netural form) and a predicted fish BCF value of 36 L/Kg. Both of these values are below the log Kow 4.0 and BCF 500 threshold limits for classification as potentially bioaccumulative. The substance therefore is assessed as not B i.e. not potentially bioaccumulative.

Chronic toxicity of 2-(diphenylphosphino)benzoic acid to freshwater invertebrates has been investigated in a historical study. The 21d NOEC for the substance was established to be 0.32 mg/L. Therefore the substance does not meet the criteria for classification as T based on an assessment of the available ecotoxicity data. [Need to include statement on mammalian tox]

Likely routes of exposure:

Human Health:

Dermal/Inhalation

Environment:

Wastewater effluent and rainfall run-off

Deposition on surface water and soil following release to atmosphere