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EC number: 201-321-0 | CAS number: 81-07-2
Endpoint summary
Administrative data
Description of key information
Additional information
Biodegradation:
The ready biodegradability study results (UERL) on the close read-across (sodium saccharin) indicates that the substance is moderately biodegradable. Further this is supported by the ultimate biodegradation estimate in the Biowin model (EPI suite version 4.1) shows that the current compound is moderately biodegradable (biowin 2=0.6, biowin 3=2.8, biowin<0.5).
The summary of the results are presented below
Sr.No |
Test Type |
Percentage Degradation |
Half - Life |
Parameter |
Sources |
1 |
Ready biodegradability |
50% degradation |
15 days |
Half-life |
Predicted data from PBT profiler |
2 |
Ready biodegradability |
58.2714 % degradation |
- |
O2 consumption |
Predicted data from QSAR |
By applying weight of evidence approach to the target chemical 1,2-benzisothiazol-3(2H)-one 1,1-dioxide it was found that the degradation percentage of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide in water medium is 50 to 58%.This result in ready biodegradability of the chemical.
Biodegradation in water and sediment
No. of studies reviewed for Biodegradation in water and sediment from reliable sources having Klimisch rating 2.
The summary of the results are presented below
Sr.No |
Endpoint |
Percentage Degradation |
Half - Life |
Parameter |
Sources |
1. |
Ready biodegradability |
90% degradation |
Sediment-7 days |
Test material analysis |
Experimental data from Environmental Science & Technology;2014 |
2. |
Ready biodegradability |
50% degradation |
Water-15 days
Sediment-140 days |
Half-life |
Predicted data from PBT profiler |
3. |
Ready biodegradability |
50% degradation |
Water-15 days
Sediment-135 days |
O2 consumption |
Predicted data from EPI suite |
By applying weight of evidence approach to the target chemical 1,2-benzisothiazol-3(2H)-one 1,1-dioxide it was found that the degradation percentage of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide in water and sediment medium in the range 50 to 90%.This result in ready biodegradability of the chemical.
Biodegradation in soil
No. of studies reviewed for Biodegradation in soil from reliable sources having Klimisch rating 2.
The summary of the results are presented below
Sr.No |
Endpoint |
Half life |
Parameter |
Result |
Sources |
1 |
Biodegradation in soil |
30 days |
Half-life |
Not persistent (Readily biodegradable) |
Predicted data from PBT profiler and EPI suite |
2 |
Biodegradation in soil |
30.2 days |
DT50(Dissipation time) |
Not persistent (Readily biodegradable) |
Predicted data from QSAR |
By applying weight of evidence approach to the target chemical,thedegradation of parent compound 1,2-benzisothiazol-3(2H)-one 1,1-dioxide in soil was estimated as 50 percent in 30 to 30.2 days whichdoes not exceeds the EPA criteria of >= 2 months (and <= 6 months). Therefore, 1,2-benzisothiazol-3(2H)-one 1,1-dioxide is estimated not to be persistent in the soil environment.
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