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Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature is available. There are no information on the testing procedure nor on the substance composition.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
RTECS Database
Year:
2016
Bibliographic source:
RTECS Database
Reference Type:
review article or handbook
Title:
Prehled Prumyslove Toxikologie.
Author:
Marhold, J.
Year:
1986
Bibliographic source:
Organicke Latky. Prague, Czechoslovakia, Avicenum. 291

Materials and methods

Principles of method if other than guideline:
Data from secondary sources; Standard Draize Test.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit

Test system

Amount / concentration applied:
500 mg
Observation period:
24 hours

Results and discussion

In vivo

Results
Remarks on result:
other: Mild irritation
Irritant / corrosive response data:
Mild irritant

Applicant's summary and conclusion

Conclusions:
Mild irritant
Executive summary:

Data from secondary sources; no further details about testing method and procedures are available. The substance was applied on the skin of rabbits and after 24 hours the skin resulted mildly irrititated.