Registration Dossier

Administrative data

Endpoint:
repeated dose toxicity: other route
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not translated, only short abstract available

Data source

Reference
Title:
No information
Author:
Kosachevskaya, P.I., Gig. Toksikol. Pestits. Klin.|Otravkenii 5, 92-99 (1967)

Materials and methods

Principles of method if other than guideline:
migrated dataset
GLP compliance:
no
Remarks:
GLP was not mandatory at the time of the study

Test material

Constituent 1
Chemical structure
Reference substance name:
3-nitrotoluene
EC Number:
202-728-6
EC Name:
3-nitrotoluene
Cas Number:
99-08-1
Molecular formula:
C7H7NO2
IUPAC Name:
1-methyl-3-nitrobenzene

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: other
Duration of treatment / exposure:
20 d
Frequency of treatment:
daily
Doses / concentrations
Remarks:
Doses / Concentrations:
1/5 LD50
Control animals:
other: keine Angabe
Details on study design:
Post-exposure period: no data

Results and discussion

Effect levels

Dose descriptor:
NOAEC
Effect level:
other: migrated dataset
Sex:
not specified
Basis for effect level:
other: migrated dataset
Remarks on result:
not determinable
Remarks:
no NOAEC identified

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables

Freetext:
no cumulative effect observed

Applicant's summary and conclusion