Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: other route
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not translated, only short abstract available

Data source

Reference
Title:
No information
Author:
Kosachevskaya, P.I., Gig. Toksikol. Pestits. Klin.|Otravkenii 5, 92-99 (1967)

Materials and methods

GLP compliance:
no
Remarks:
GLP was not mandatory at the time of the study

Test material

Constituent 1
Chemical structure
Reference substance name:
3-nitrotoluene
EC Number:
202-728-6
EC Name:
3-nitrotoluene
Cas Number:
99-08-1
Molecular formula:
C7H7NO2
IUPAC Name:
3-nitrotoluene

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: other
Duration of treatment / exposure:
20 d
Frequency of treatment:
daily
Doses / concentrations
Remarks:
Doses / Concentrations:
1/5 LD50
Control animals:
not specified
other: keine Angabe
Details on study design:
Post-exposure period: no data

Results and discussion

Effect levels

Dose descriptor:
NOAEC
Effect level:
other:
Sex:
not specified
Basis for effect level:
other:
Remarks on result:
not determinable
Remarks:
no NOAEC identified

Target system / organ toxicity

Critical effects observed:
not specified

Any other information on results incl. tables

no cumulative effect observed

Applicant's summary and conclusion