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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: long-term
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data from conference poster, full study not available

Data source

Reference
Reference Type:
other: conference poster
Title:
Toxicity of seven different nanoparticles to Eisenia fetida.
Author:
Heckman et al.
Year:
2008
Bibliographic source:
SETAC 25-29 May, 2008, Warsaw, Poland

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 222 (Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei))
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
* TiO2 nanoparticles (from Evonik Degussa), nominal particle size 21 nm, surface area 50 m²/g.
* bulk TiO2

Test organisms

Test organisms (species):
Eisenia fetida
Animal group:
annelids

Study design

Study type:
laboratory study
Substrate type:
natural soil
Limit test:
yes
Total exposure duration:
4 wk
Post exposure observation period:
hatching of produced cocoons was monitored during the following 4 weeks

Test conditions

Details on test conditions:
4 replicates
Nominal and measured concentrations:
nominal: 1000 mg/kg dry soil

Results and discussion

Effect concentrationsopen allclose all
Duration:
4 wk
Dose descriptor:
NOEC
Effect conc.:
>= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
TiO2 nanoparticles
Basis for effect:
other: cocoon production
Remarks on result:
other: +/- 20% effect
Duration:
8 wk
Dose descriptor:
LOEC
Effect conc.:
<= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
TiO2 nanoparticles
Basis for effect:
other: hatchability
Remarks on result:
other: +/- 25% effect
Duration:
8 wk
Dose descriptor:
LOEC
Effect conc.:
<= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
TiO2 nanoparticles
Basis for effect:
other: juvenile production
Remarks on result:
other: +/- 50% effect
Duration:
4 wk
Dose descriptor:
NOEC
Effect conc.:
>= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
bulk TiO2
Basis for effect:
other: cocoon production
Duration:
8 wk
Dose descriptor:
NOEC
Effect conc.:
>= 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
bulk TiO2
Basis for effect:
other: hatchability and juvenile production
Details on results:
data derived from graph

Applicant's summary and conclusion