Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted following OECD and GLP guidelines

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report Date:
2001

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Deviations:
no
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
ca. 118 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
ca. 45 mg/L
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
growth rate

Any other information on results incl. tables

-

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The NOEC of Isopropenylmethylether for both growth inhibition and growth rate reduction corresponds with an initial concentration of 118 mg/l and a mean measured concentration of 45 mg/l based on the whole test period of 72 hours.
Executive summary:

Isopropenylmethylether did not inhibit growth of the fresh water algae species Selenastrum capricornutum at nominal loadings up to and including 200 mg/l. Based on an extra peak appearing in the chromatogramms, which increased in time, the substance was probably not hydrolytically stable. Altough the initial concentrations were significantly lower than the nominal, the initial concentrations exceed 100 mg/l at the highest nominal loading of 200 mg/l. The data further indicated a tendency to stimulation of algal growth proportional to the loading of the substance.