Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: study performed according to OECD and GLP guidelines

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report Date:
2000

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
ca. 1.7
Temp.:
21 °C

Any other information on results incl. tables

-

Applicant's summary and conclusion

Conclusions:
The partition coefficient (n-octanol/water) of Isopropenyl methyl ether is:
Pow= 50.8 (log Pow= 1.7).
Test temperature: 21.0 ± 1.5°C.
Executive summary:

From the structural formula of Iso propenyl methyl ether, the logarithm of the partition coefficient (n-octanol/water), log Pow, was calculated to be 0.50 using the Rekker calculation method. Therefore, the flask-shaking method was chosen for the determination of the partition coefficient ( (n-octanol/water) of Isopropenyl methyl ether.

The results of the calculation method and the Flask-shaking method are not in agreement. Since the Flask-shaking method is a more accurate method than the calculation method, the results of the Flask-shaking method are reported as the partition coefficient (n-octanol/water) of Isopropenyl methyl ether. The partition coefficient (n-octanol/water) of Isopropenyl methyl ether is 50.8 (log Pow= 1.7) at 21.0 ± 1.5°C.