Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

Currently viewing:

Administrative data

PBT assessment: overall result

Type of composition:
legal entity composition of the substance
State / form:
Reference substance:
Reference substance:
Reference substance:
Reference substance:
PBT status:
further information relevant for the PBT assessment is necessary

The PBT assessment will be further updated once the study results originating from requests in the SEv final decison are available.


Five isomers of ditolyl ether (2,3' -, 2,4' -, 3,3' -, 3,4' -, and 4,4' -DTE) do not fulfill the definitve criteria of a persistent (P) or very persistent (vP) substance based on the findings of the OECD 309 guideline study with DT50 values below 40 days at 12°C. One isomer (2,2' -DTE), which is an impurity, however shows a DT50 of 63 days (geometric mean of 2 results) at 12°C leading to the conclusion as vP. Based on read across and weight of evidence the five isomers do not fulfill the criteria of a bioaccumulative substance (B, vB). The bioaccumulation behaviour of the 2,2'-isomer will be determined in a follow-up OECD 305 test. Finally, based on the available studies on acute and chronic toxicity to the environment as well as on human health it does not fulfill the criteria of a toxic substance (T).

In conclusion, ditolyl ether currently does not fulfill the criteria as a PBT or vPvB substance.