Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 248-948-6 | CAS number: 28299-41-4
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Dimethyldiphenylether
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- Dimethyldiphenylether
- Reference substance:
- Dimethyldiphenylether
- Reference substance:
- Dimethyldiphenylether
- Reference substance:
- Dimethyldiphenylether
- PBT status:
- further information relevant for the PBT assessment is necessary
- Justification:
The PBT assessment will be further updated once the study results originating from requests in the SEv final decison are available.
____
Five isomers of ditolyl ether (2,3' -, 2,4' -, 3,3' -, 3,4' -, and 4,4' -DTE) do not fulfill the definitve criteria of a persistent (P) or very persistent (vP) substance based on the findings of the OECD 309 guideline study with DT50 values below 40 days at 12°C. One isomer (2,2' -DTE), which is an impurity, however shows a DT50 of 63 days (geometric mean of 2 results) at 12°C leading to the conclusion as vP. Based on read across and weight of evidence the five isomers do not fulfill the criteria of a bioaccumulative substance (B, vB). The bioaccumulation behaviour of the 2,2'-isomer will be determined in a follow-up OECD 305 test. Finally, based on the available studies on acute and chronic toxicity to the environment as well as on human health it does not fulfill the criteria of a toxic substance (T).
In conclusion, ditolyl ether currently does not fulfill the criteria as a PBT or vPvB substance.
Reference
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
