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Toxicity to microorganisms

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Description of key information

No inhibition of respiration of activated sludge was observed up to 100 mg/L the highest tested concentration in an OECD 209 compliant study.

Key value for chemical safety assessment

Additional information

The effect of the test item on bacteria was assessed according to OECD 209 by measuring the micro-organisms respiration rate on a sample of activated sludge during an incubation period of 3 hours.


 EC50- 3h 4-methylthiosemicarbazide > 100mg/L, and NOEC < 5 mg/L


4-methylthiosemicarbazide did not show any effect on the respiration of activated sludge in the conditions of the test up to a concentration of 100 mg/L.