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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

According to PBT profiler 3-oxoglutaric acid is 50% biodegradable in water in 8.7 days (half-life).
Also from QSAR prediction it is found that the substance degrades about 77.4% in 28 days.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

No. of studies reviewed for biodegradation in water and presented as weight of evidence; from reliable sources having Klimish rating 2 indicate the chemical 3 -oxoglutaric acid to be readily bio-degardable.

The summary of the results are presented below


Sr. No

Endpoint name





% degradation 50 % in 8.7 days


 % degradation  77.4  %   in 28 days


A different QSAR model (VegaNIC) also predicted the chemical to be bio-degradable. Thus, based on the weight of evidence approach, the chemical 3 -oxoglutaric acid is concluded to be bio-degaradable.