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Diss Factsheets
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EC number: 272-379-2 | CAS number: 68815-51-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Acute oral toxicity: LD50, rat: > 2000 mg/kg bw
Acute dermal toxicity: LD50, rat: > 2000 mg/kg bw
Acute inhalation toxicity: There are no data available concerning acute inhalation toxicity.
Key value for chemical safety assessment
Additional information
Oral:
In the key study that was performed according to OECD guideline 423 in compliance with GLP in male and female Sprague-Dawley rats the LD50 was determined to be > 2000 mg/kg bw (BASF AG, 2007). No mortality occured. The only observed clinical sign was slight piloerection shortly after dosing. Nothing abnormal was detected concerning body weight and gross pathology.
Dermal:
In the key study that was performed according to OECD guideline 402 in compliance with GLP in male and female Wistar rats the LD50 was determined to be > 2000 mg/kg bw (BASF SE, 2009). No mortality occured. No systemic clinical signs were observed during clinical examination. The mean body weight of the female animals did not adequately increase during the first post-exposure observation week, probably due to the bandage procedure, but increased during the second week. The mean body weight of the male animals increased throughout the study period. No macroscopic pathologic abnormalities were noted in the animals (5 males and 5 females) examined on the last day of observation. Local skin effects (erythema, edema, scaling and encrustations) were observed one day after application of the substance through to the end of the observation period.
Inhalation:
There are no data available concerning acute inhalation toxicity.
Justification for classification or non-classification
GHS classification according to Annex I 1272/2008 CLP (EU GHS):
- Oral route: conclusive, but not sufficient for classification
- Dermal route: conclusive, but not sufficient for classification
- Inhalation route: data lacking
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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