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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation / corrosion
Remarks:
other: SAR prediction.
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2007
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well-documented
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
publication
Title:
Evaluation of SARs for the prediction of skin irritation/corrosion potential: structural inclusion rules in the BfR decision support system
Author:
Saliner, A. G.; Tsakovska, I.; Pavan, M.; Patlewicz, G.; Worth, A. P.
Year:
2007
Bibliographic source:
SAR QSAR Environ Res, 18, (3-4), 331-42

Materials and methods

Principles of method if other than guideline:
SARs for the prediction of skin irritation/corrosion potential.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-(octanoyloxy)propyl octanoate
EC Number:
700-003-3
Cas Number:
56519-71-2
Molecular formula:
C19 H36 O4
IUPAC Name:
3-(octanoyloxy)propyl octanoate

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
other: Unknown
Conclusions:
Prediction of the irritating properties of 1,3-Propanediol Dicaprylate applying TOXmatch was not successful because the outcome of the prediction was "Unknown".