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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

Acutely very toxic for aquatic invertebrates

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
0.015 mg/L

Additional information

Effects of the test item on mobility of daphnids were investigated in a 48 -h static study on Daphnia magna under GLP conditions and following OECD TG 202. Due to the low water solubility, the test concentrations were prepared as water accomodated fractions (WAF) as described in OECD TG 23. The analysis of test concentrations was conducted by GC-MS; the results are expressed as mean measured concentrations. The 48 -h EC50 based on measured test item concentrations on was 0.015 mg/L (Petersen et al., 2010). The study was considered as key study.

Moreover, effects on daphnids were determined in two elder studies performed similarly to nowadays methods (according to DIN 38412, L11), but without analytical monitoring. Based on nominal concentrations, the 48 -h EC50 values on Daphnia magna were extrapolated by linear regression analysis to be 0.7 mg/L (BASF AG, 1989) and 0.08 mg/L respectively (Amann, 1989). These studies were considered as supporting studies.