Registration Dossier
Registration Dossier
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EC number: 610-954-5 | CAS number: 53075-09-5
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The substance is not biodegradable and poorly eliminated from water
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
In a CO2/DOC combination test under enhanced test conditions according to ISO DIS 9439 using the analogous substance amantadine hydrochloride a biodegradation of less than 10% was determined after an exposure period of 60 days (BASF SE, 2012). This read-across os valid as the core part of the molecule is the same. This core part is assumed to persist to microbial degradation due to its complex structure. Additionally, tests on the inherent biodegradability are available for an aqueous solution of adamantyltrimethylammoniumhydroxid (BASF AG, 2007), an aqueous solution of N,N,N-trimethyl-1-adamantanaminium sulfate (BASF AG, 2008) and for –adamantyldimethylamine (BASF AG, 2007). Again, all these molecules consist of the same core part of the molecule. In all tests an elimination from water of less than 10% was observed during the exposure period. Therefore adamantan and its derivatives with a comparable core part of the molecule have to be considered as not biodegradable.
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