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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given Limited information concerning test conditions and/or experimental methods

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1970
Reference Type:
study report
Title:
Unnamed
Year:
1999
Reference Type:
secondary source
Title:
SIDS Category of Alkyl sulfates, Alkane sulfonates and Alpha-olefin sulfonates
Author:
OECD
Year:
2007
Bibliographic source:
UNEP Publications

Materials and methods

Principles of method if other than guideline:
Method: other
GLP compliance:
no
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Purity:
46-49 % active substance, balance being water

Chain Length Distribution:
C8: 8.5%
C10: 8.5%
C12: 68%
C14: 25%
C16: 6%

Test animals

Species:
rat
Strain:
Wistar
Sex:
male

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
not specified
Doses:
single application of increasing doses (not further specified)
No. of animals per sex per dose:
10

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
> 3 625 mg/kg bw
Based on:
act. ingr.

Any other information on results incl. tables

LD50 given with 7.94 mL/kg

CLINICAL SIGNS: abdominal position, decreased motility, apathy

NECROPSY FINDINGS: no data

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU