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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Readily biodegradable: 64% (ThCO) in 28 days (OECD 301 B)

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

One study investigating the ready biodegradability of the structural similar substance amides, C16-C18 (even numbered) and one study on the structural related substance (Z)-Docos-13-enamide are available (Mead, 2001a and Mead, 2001b). It is therefore considered valid to read-across the results for Amides, C16-C18 (even numbered) and (Z)-Docos-13-enamide to fill the data gap for docosanamide (CAS No. 3061-75-4).

The tests were carried out according to the OECD Guideline No. 301B: Ready Biodegradability: CO2 Evolution Test (1992), under GLP conditions. Both substances reached a biodegradation value of > 60% after 28 days. However, the degradation values of 62 % and 64 % were not reached within the 10-d window, but as the substances are a mixture of constituents with different chain-lengths, sequential biodegradation of the individual structures is taking place. Due to a degradation of > 60% within 28 days the substance can be regarded as readily biodegradable. The 10 -day window should not be applied to interpret the test results (Annex I, OECD Guideline for The Testing of Chemicals 'Revised introduction to the OECD guidelines for testing of chemicals, section 3, OECD, March 2006). Further information will not be required for the assessment;docosanamide (CAS No. 3061-75-4)can be regarded as readily biodegradable.