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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

Currently viewing:

Administrative data

Endpoint:
skin sensitisation
Remarks:
in vivo
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 98-42-0
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-Commercial

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling Database
Principles of method if other than guideline:
Multicase model A33
GLP compliance:
no
Type of study:
other: Estimation

Test material

Constituent 1
Chemical structure
Reference substance name:
3-amino-4-methoxybenzenesulphonic acid
EC Number:
202-667-5
EC Name:
3-amino-4-methoxybenzenesulphonic acid
Cas Number:
98-42-0
Molecular formula:
C7H9NO4S
IUPAC Name:
3-amino-4-methoxybenzenesulfonic acid

In vivo test system

Test animals

Species:
other: Guinea pig or human
Strain:
not specified
Sex:
not specified

Study design: in vivo (non-LLNA)

Inductionopen allclose all
Route:
other: no data
Vehicle:
no data
Concentration / amount:
no data
Challengeopen allclose all
Route:
other: no data
Vehicle:
no data
Concentration / amount:
no data
No. of animals per dose:
no data
Positive control substance(s):
not specified

Study design: in vivo (LLNA)

Vehicle:
not specified

Results and discussion

In vivo (non-LLNA)

Results
Reading:
1st reading
Group:
test chemical
No. with + reactions:
0
Clinical observations:
Non sensitising
Remarks on result:
other: Reading: 1st reading. Group: test group. No with. + reactions: 0.0. Clinical observations: Non sensitising.

Any other information on results incl. tables

Non sensitising

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
3-amino-4-methoxybenzenesulphonic acid is estimated to be non sensitising to skin
Executive summary:

3-amino-4-methoxybenzenesulphonic acid is estimated to be non sensitising to skin