Registration Dossier
Registration Dossier
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EC number: 200-087-7 | CAS number: 51-28-5
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data have been obtained from secondary source.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- Hazardous Substances Data Bank (HSDB)
- Year:
- 2 012
- Bibliographic source:
- Hazardous Substances Data Bank (HSDB)
- Reference Type:
- review article or handbook
- Title:
- No information
- Author:
- National Research Council.
- Year:
- 1 981
- Bibliographic source:
- Drinking Water & Health, Volume 4. Washington, DC: National Academy Press., p. 236, 1981
Materials and methods
- Principles of method if other than guideline:
- The method has not been specified.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,4-dinitrophenol
- EC Number:
- 200-087-7
- EC Name:
- 2,4-dinitrophenol
- Cas Number:
- 51-28-5
- Molecular formula:
- C6H4N2O5
- IUPAC Name:
- 2,4-dinitrophenol
Constituent 1
Test animals
- Species:
- dog
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Doses:
- 20 to 30 mg/kg
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 20 - 30 other: mg/kg
Any other information on results incl. tables
The lethal dose LD50 on dog is 20 to 30 mg/kg. This value has been taken from table. Details of toxic effects have not been reported other than lethal dose value.
Applicant's summary and conclusion
- Conclusions:
- The acute oral toxicity test defined a lethal dose LD50 on cat of 20 - 30 mg/kg, but details of toxic effects have not been reported other than lethal dose value. This value has been taken from table.
- Executive summary:
Data have been obtained from secondary source that mentions National Research Council. Drinking Water & Health, Volume 4. Washington, DC: National Academy Press, 1981., p. 236. The method used has not been specified and data have been taken from table.
The lethal dose LD50 on dog is 20 to 30 mg/kg, but details of toxic effects have not been reported other than lethal dose value.
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