Registration Dossier
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EC number: 200-087-7 | CAS number: 51-28-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
An inkling of toxicity of 2,4-dinitrophenol on microrganisms were found on biodegradation studies. In an aerobic biodegradation and in a biodegradation under methanogenic conditions with anaerobic digester sludge studies also a toxic level of c.a 10 -20 mg/L of 2,4-dinitrophenol was defined. A detailed study on sludge activity indicates a NOEC (no inhibitory effect) of 4 ppm of 2,4-dinitrophenol.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 4 mg/L
Additional information
Inkling of toxicity of 2,4-dinitrophenol on microrganisms were found on biodegradation studies. In an aerobic biodegradation and in a biodegradation under methanogenic conditions with anaerobic digester sludge studies also a toxic level of c.a 10 -20 mg/L of 2,4-dinitrophenol was defined (O'Connor and Young, 1989). Furthermore, in another study it has explained that little or no inhibitory effect were observed at concentration <= 20 mg/L (Tabak et al., 1981).
A detailed study on sludge activity indicates a NOEC (no inhibitory effect) of 4 ppm of 2,4-dinitrophenol. This value it ha been considered as the most relevant and conservative (Linvil G. Rich and Oscar W. Yates, JR. The Effect of 2, 4-Dinitrophenol on Activated Sludge, Sanitary Engineering Division, Department of Civil Engineering, Virginia Polytechnic Institute, Blacksburg, Virginia, 1954).
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