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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

The majority of data have been obtained from secondary source (EPA databank).

For 2,4 -dinitrophenol data for fresh and marine ecosystems are available for all three trophic levels (alga, crustacean and fish). Furthermore data on microorganisms and other aquatic organisms are also available.

On the base on ecotoxicity data, 2,4 -dinitrophenol is very toxic to aquatic for algae and crustaceans, but especially for fish. 

In fact, the most conservative LC50 and NOEC for freshwaterfish are 390 µg/L and 208 µg/L, respectively. The most conservative data on algae and crustaceans are in any case low, on the range of 1 -5 mg/L.

The same toxicity can be observed for marine water, with an LC50 fish of 1500 µg/L , a NOEC fish of 940 µg/L and a range of toxicity for algae and crustaceans of 5- 20 mg/L.

2,4-dinitrophenol is very toxic also for biodegrader microrganisms. In an aerobic biodegradation and in a biodegradation under methanogenic conditions with anaerobic digester sludge studies the toxic level of c.a 10 -20 mg/L of 2,4-dinitrophenol was defined, and a detailed study on sludge activity has setted a NOEC (no inhibitory effect) at 4 ppm of 2,4-dinitrophenol.

2,4- dinitrophenol can be harmful for other aquatic organisms as data on Aedes aegypti Yellow Fever Mosquito Chironomids as Tanytarsus dissimilis Midge show (LC50 5-10 mg/L and LC50 of 48.1 mg/L, respectively). This latter organism, in its first larval stage, lives also in sediment.