Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

High quality test data is available on the acute toxicity of nickel slag and surrogate substance (copper slag) to algae. Lowest short-term toxicity value observed is greater than 100 mg/l

Key value for chemical safety assessment

Additional information

Reliable GLP studies (Wenzel, 2010) were performed on the analogue substance (copper slag) to determine the toxicity of mesocosm water extracts of five different slags and one basalt control on the growth of the unicellular fresh water green algae Pseudokirchneriella subcapitataand diatom Navicula pelliculosaexposed for a test period of 72 hours under static conditions according to OECD 201(‎1). EC50 values in the range of 155 mg/l to 965 mg/l forP. subcapitata)and in the range of 1047 to 4474 mg/l forN. pelliculosawere assessed. EC10 values in the range of 87.9 mg/l to 340 mg/l forP. subcapitataand in the range of 795 mg/l to 3426 mg/lN. pelliculosawere assessed. Typical slag samples have been tested with composition similar to the composition of nickel slag as outlined in IUCLID Section 1.2.

A further OECD 201 guideline study (Sauerwald and Weiss, 2004) investigated the toxicity of the analogue substance(copper slag) onalgaein a 72h growth inhibition test. No toxic effects were observed at tested concentrations. IC 10 and IC 50 values of > 100 g/l were assessed Typical slag samples have been tested with composition similar to the composition of nickel slag as outlined in IUCLID Section 1.2.

The calculated classification of nickel slag via Toxic Unit approach (Higher Tier Arche CLP Tool) resulted in No Acute classification for the UVCB substance. Based on this result, the related criteria provided the estimated value for toxicity to aquatic algae (see EU CLP Annex I Table 4.1.0):72hr ErC50 (for algae) >100 mg/l

Using a weight of evidence approach, the lowest short-term toxicity acute toxicity of nickel slag to algae is greater than 100 mg/l which means No classification.