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Based on the overall information available for thioglycolic acid, its salts and its main degradation (via oxidation) product, the substances can be considered as of low toxicity for aquatic species. The information available for the anionic form allows to conclude that the thioglycolate is harmful to Daphnia magna only. Acute ecotoxicity knowledge is strengthened by information existing on diammonium dithioglycolate which is the main degradation product of thioglycolic acid. Diammonium dithioglycolate occurs rapidly in the environment based on practical case (Devaux, 2003) and therefore this case is a good surrogate for the thioglycolate ecotoxicity. On this basis it can be concluded that the thioglycolate anion is neither toxic nor harmful for algae. Diammonium dithioglycolate data also exists for Daphnia and demonstrates that this form is neither toxic nor harmful for Daphnia. Additionally, it can be considered that the thioglycolate anion is of no concern for Daphnia based on its half-life in water. Nevertheless as valid experimental data exists on the thioglycolic acid, the applicant prefers to retain this result and concludes that thioglycolic acid is harmful to Daphnia.