Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
2 mg/L
Assessment factor:
10

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no hazard identified

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Aquatic environment classification

L-Tryptophan proved to be readily biodegradable (77% biodegradation after 28 d).

The lowest acute EC/LC50 value in aquatic tests is the L(E)C50>100 mg/L for algae and daphnids.

Due to the fact that L-tryptophan is proven to be readily biodegradable and its low log Kow (-1.06) the substance is not classified as dangerous/hazardous for the environment according to Directive 67/548/EEC and according to the Regulation (EC) 1272/2008 on classification, labelling and packaging of substances and mixtures (CLP Regulation):

Lowest reliable L(E)C50 value:                 >100 mg/L algae, daphnids

Ready biodegradable                                yes

log Pow                                                    < 3

Special concern:                                        no

 

According to 67/548/EEC Annex 1:      not classified

 

According to GHS:

Hazardous to the environment      not classified, no hazard statement

                                                      Reason for classification:    L(E)C50: > 100 mg/L; readily biodegradable, log Pow<4

Hazardous to the atmospheric environment:

(Hazardous to the ozone layer: This includes substances which are listed in Annex I to Regulation (EC) No 2037/2000 of the European Parliament and of the Council of substances that deplete the ozone layer (1) and its subsequent amendments):

L-Tryptophan is not listed in Annex I of (EC) No 2037/2000.

 

M-Factor:                                      No

Labelling:                                        No Signal word and Pictogram for environmental hazards