Trichlorotrifluoroethane

Biodegradation in water: screening tests

Administrative data

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Limited documentation. Read-across

Data source

Reference

Reference Type:

publication

Title:

Unnamed

Year:

1991

Report date:

1991

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))

Principles of method if other than guideline:

Improved type for a volatile substance

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

1,1,2-trichlorotrifluoroethane

EC Number:

200-936-1

EC Name:

1,1,2-trichlorotrifluoroethane

Cas Number:

76-13-1

IUPAC Name:

1,1,2-trichloro-1,2,2-trifluoroethane

Details on test material:

- Molecular formula: C2Cl3F3 (identical to submission substance)
- Molecular weight: 187.376 g/mol (identical to submission substance)
- Smiles notation: ClC(F)(F)C(Cl)(Cl)F (different from submission substance)
- InChl: InChI=1S/C2Cl3F3/c3-1(4,6)2(5,7)8 (different from submission substance)
- Structural formula: see attachment CAS_76-13-1_Structure.png (under "Illustration (picture/graph)")
- Physical state: liquid

Study design

Oxygen conditions:

not specified

Inoculum or test system:

activated sludge (adaptation not specified)

Duration of test (contact time):

4 wk

Initial test substance concentration

Initial conc.:

100 mg/L

Parameter followed for biodegradation estimation

Parameter followed for biodegradation estimation 1

Parameter followed for biodegradation estimation:

test mat. analysis

Parameter followed for biodegradation estimation 2

Parameter followed for biodegradation estimation:

other: BOD

Details on study design:

concentration of test substance: 100 ppm (i.e. 100 mg/L)
concentration of activated sludge: 30 ppm (i.e. 30 mg/L)

Results and discussion

% Degradation

% Degradation 1

Parameter:

% degradation (test mat. analysis)

Value:

0

Sampling time:

4 wk

% Degradation 2

Parameter:

other: BOD

Value:

2

Sampling time:

4 wk

Applicant's summary and conclusion

Validity criteria fulfilled:

not specified

Interpretation of results:

under test conditions no biodegradation observed

Conclusions:

In an OECD TG 301C test (MITI-I) the test substance 1,1,2-trichloro-1,2,2-trifluoroethane was not readily biodegradable.

The biodegradability of the target chemical 1,1,1-trichloro-2,2,2-trifluoroethane is determined by read-across from an OECD TG 301C test with the source chemical 1,1,2-trichloro-1,2,2-trifluoroethane. The analogue approach is justified in Section 13 (Assessment Reports_Read-Across, in attachment CAS_354-58-5_Read-Across.pdf). As a consequence 1,1,1-trichloro-2,2,2-trifluoroethane is not readily biodegradable.

Executive summary:

In an OECD TG 301C test (MITI-I) the test substance 1,1,2-trichloro-1,2,2-trifluoroethane was not readily biodegradable.

The biodegradability of the target chemical 1,1,1-trichloro-2,2,2-trifluoroethane is determined by read-across from an OECD TG 301C test with the source chemical 1,1,2-trichloro-1,2,2-trifluoroethane. The analogue approach is justified in Section 13 (Assessment Reports_Read-Across, in attachment CAS_354-58-5_Read-Across.pdf). As a consequence 1,1,1-trichloro-2,2,2-trifluoroethane is not readily biodegradable.