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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Limited documentation. Read-across

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1991
Report Date:
1991

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
Principles of method if other than guideline:
Improved type for a volatile substance
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Molecular formula: C2Cl3F3 (identical to submission substance)
- Molecular weight: 187.376 g/mol (identical to submission substance)
- Smiles notation: ClC(F)(F)C(Cl)(Cl)F (different from submission substance)
- InChl: InChI=1S/C2Cl3F3/c3-1(4,6)2(5,7)8 (different from submission substance)
- Structural formula: see attachment CAS_76-13-1_Structure.png (under "Illustration (picture/graph)")
- Physical state: liquid

Study design

Oxygen conditions:
not specified
Inoculum or test system:
activated sludge (adaptation not specified)
Duration of test (contact time):
4 wk
Initial test substance concentration
Initial conc.:
100 mg/L
Parameter followed for biodegradation estimationopen allclose all
Parameter followed for biodegradation estimation:
test mat. analysis
Parameter followed for biodegradation estimation:
other: BOD
Details on study design:
concentration of test substance: 100 ppm (i.e. 100 mg/L)
concentration of activated sludge: 30 ppm (i.e. 30 mg/L)

Results and discussion

% Degradationopen allclose all
Parameter:
% degradation (test mat. analysis)
Value:
0
Sampling time:
4 wk
Parameter:
other: BOD
Value:
2
Sampling time:
4 wk

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
In an OECD TG 301C test (MITI-I) the test substance 1,1,2-trichloro-1,2,2-trifluoroethane was not readily biodegradable.

The biodegradability of the target chemical 1,1,1-trichloro-2,2,2-trifluoroethane is determined by read-across from an OECD TG 301C test with the source chemical 1,1,2-trichloro-1,2,2-trifluoroethane. The analogue approach is justified in Section 13 (Assessment Reports_Read-Across, in attachment CAS_354-58-5_Read-Across.pdf). As a consequence 1,1,1-trichloro-2,2,2-trifluoroethane is not readily biodegradable.
Executive summary:

In an OECD TG 301C test (MITI-I) the test substance 1,1,2-trichloro-1,2,2-trifluoroethane was not readily biodegradable.

The biodegradability of the target chemical 1,1,1-trichloro-2,2,2-trifluoroethane is determined by read-across from an OECD TG 301C test with the source chemical 1,1,2-trichloro-1,2,2-trifluoroethane. The analogue approach is justified in Section 13 (Assessment Reports_Read-Across, in attachment CAS_354-58-5_Read-Across.pdf). As a consequence 1,1,1-trichloro-2,2,2-trifluoroethane is not readily biodegradable.