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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
calculation (if not (Q)SAR)
Remarks:
estimated by calculation
Adequacy of study:
key study
Study period:
Start date of the experimental work: 17/06/2009 and Completion date of the experimental work: 13/07/2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Estimation based on calculation
Qualifier:
no guideline followed
Principles of method if other than guideline:
Experimental techniques are available for the determination of water solubility of a substance or preparation. These are described in EC Test A6 as Shake flask method and Column elution method. However, the A6 test cannot to be carried out because the sample reacts with water. As a result, an estimation based on calculation has been carried out.
GLP compliance:
no
Type of method:
other: by calculation
Remarks on result:
other: 1.45e-16 g.L-1 Estimated and 2.20 E-13 g.L-1 Estimated using Meylan Equations
Details on results:
1.45e-16 g.L-1 Estimated (2.20 E-13 g.L-1 Estimated using Meylan Equations)
Conclusions:
Experimental techniques are available for the determination of water solubility of a substance or preparation. These are described in EC Test A6 as Shake flask method and Column elution method. However, the A6 test cannot to be carried out because the sample reacts with water. As a result, an estimation based on calculation has been carried out.
The water solubility was therefore calculated to be 1.45e-16 g.L-1 Estimated and 2.20 E-13 g.L-1 Estimated using Meylan Equations.

Description of key information

The water solubility was calculated to be 1.45E-16 g.L-1 Estimated and 2.20E-13 g.L-1 Estimated using Meylan Equations.

Key value for chemical safety assessment

Additional information