Registration Dossier
Registration Dossier
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EC number: 259-715-3 | CAS number: 55589-62-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (Zebra fish, 96 h) = 1800 - 2500 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1 800 mg/L
Additional information
In two non-GLP-studies, conducted with Zebra fish and Orfe, respectively, no mortalities were observed up to the highest test concentration of 1000 mg/L. In another study conducted with Zebra fish but under GLP conditions, no mortalities were observed at a higher test concentration of 1800 mg/L. At the next higher test concentration of 2500 mg/L, the mortality of the animals was 90%. No statistical estimation of the LC50 was performed. Therefore, the short-term toxicity of Acesulfame K to Zebra fish was given as being within the range of 1800 - 2500 mg/L. As the definite value is unknown, the lower one was chose for risk assessment purposes.
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