Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-793-6 | CAS number: 126-57-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
- Endpoint:
- toxicity to soil microorganisms
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study well documented, meets generally accepted specific principles, acceptable for assessment.
- Justification for type of information:
- The source and the target substances share structural similarities with common functional groups, esters, and side chains varying in their lenght. Moreover, the side chains are chemically simple structures which have no structural alerts for toxicity and which are closely related to substances of known low toxicity.
Data source
Reference
- Reference Type:
- publication
- Title:
- Triglyceride degradation in soil
- Author:
- Hita, C. et al.
- Year:
- 1 996
- Bibliographic source:
- Org. Geochem 25(1-2): 19-28
Materials and methods
- Principles of method if other than guideline:
- No guidelines was followed.
The degradation of the model molecule (pure tristearin) was investigated in three different soil types, to determine the behavior of fatty wastes. - GLP compliance:
- not specified
Test material
- Reference substance name:
- Glycerol tristearate
- EC Number:
- 209-097-6
- EC Name:
- Glycerol tristearate
- Cas Number:
- 555-43-1
- IUPAC Name:
- propane-1,2,3-triyl trioctadecanoate
- Details on test material:
- - Name of test material (as cited in study report): tristearin
- Analytical purity: no data
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test substrate
- Vehicle:
- no
- Details on preparation and application of test substrate:
- APPLICATION OF TEST SUBSTANCE TO SOIL
- Method: The three soil samples were first sieved (<2mm), adjusted to 2/3 of the water-holding capacity of each respective soil and then weighed into 750 cm3 flasks in portions calculated to correspond to 100 g o.d. soil. The soils were subsequently supplemented with a pure triglyceride.
Test organisms
- Test organisms (inoculum):
- soil
Study design
- Total exposure duration:
- 4 wk
Test conditions
- Test temperature:
- 20°C
- Details on test conditions:
- TEST SYSTEM
- Test container: flask
- Amount of soil: 100 g
- No. of replicates per concentration: yes, 3 replicates
- No. of replicates per control: yes, 3 replicates
VEHICLE CONTROL PERFORMED: no - Nominal and measured concentrations:
- 0.2% (wt/wt)
Results and discussion
Effect concentrations
- Key result
- Duration:
- 4 wk
- Dose descriptor:
- other: hydrolisis of the trigliceride
- Effect conc.:
- ca. 0.2 other: %
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- other: biodegradation of the test material
- Remarks on result:
- other: increased activity of soil microorganisms
Any other information on results incl. tables
The results show that, due to the soil supplementation with tristearin, free fatty acids were produced. After soil microflora adaption, these compounds are utilized as they are freed by enzymatic hydrolysis. A part of the of the monocarboxyclic acids is probably oxidized to form di-, keto- and hydroxyl-acids. Contrary the acid fractions evolution, the amounts of the neutral fractions increased between 1 and 4 weeks in the supplemental soils. This is due to the increase of the quantity of alcohols and polar neutral compounds. Bio-oxidation processes seem to be more efficient after 4 weeks. After 1 week also a low decrease, compared to the controls, in the amounts of hydrocarbons consecutive to a low increase of the ester fractions.
Main result of the monoacid fractions analysis was the rapid formation of stearic acid in considerable amounts. This result showed that an intense hydrolysis reaction with specific lipase of tristearin had occurred after the soil supplementation. The investigations of ester fractions showed that new alkanoic acids (methyl stearate, ethyl stearate, and propyl stearate), not determined in the controls, were generated in the supplemented soils. Among other processes the following hypothesis to explain the formation of these compounds were proposed:
1. Bioesterification of a part of the free stearic acid, released by an enzymatic hydrolysis reaction
2. Alcoholysis of the triglyceride to form esters, directly
3. And/or direct formation of these compounds from tristearin with C-C and C-O bond cleavages
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- To study the fate of fatty wastes left by food industries in the soil, tristearin was chosen as a model molecular marker and its biodegradation followed in different types of soil in a laboratory experiment. Samples of three soils (controls and treatments) were incubated for periods of 1–4 weeks, at 20°C. A significant disappearance of total free lipids was observed. A detailed study of different lipid classes showed an increased activity by soil microorganisms. This resulted in the oxidation and hydrolysis of the added component, producing free stearic acid and esters (methyl stearate, ethyl stearate and propyl stearate). After 4 weeks, the amounts of these compounds decreased. They are certainly intermediate components in the biodegradation processes of triglycerides. The use of this pathway for the elimination of fatty wastes in soil seems to be all the more important as it is known that fatty acids, mono/diglycerides and glycerol are removed more easily than triglycerides.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.