Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 211-560-2 | CAS number: 665-66-7
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Principles of method if other than guideline:
- External method EM/00408/01 from Competence Center Analytics, BASF SE {chapter 4: visual method) was applied to investigate
complete miscibility - GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
- Reference substance name:
- Amantadine hydrochloride
- EC Number:
- 211-560-2
- EC Name:
- Amantadine hydrochloride
- Cas Number:
- 665-66-7
- Molecular formula:
- C10H17N.ClH
- IUPAC Name:
- adamantan-1-amine hydrochloride
- Test material form:
- other: solid
- Details on test material:
- Name of test material (as cited in study report): 1-Aminoadamantanhydrochlrid
Analytical purity: 99.7 g/100g by 1H-NMR spectroscopy using the internal standard method (determined during the GLP-study No.
11 L00389 from Competence Center Analytics, BASF SE)
Lot/batch No.: 20110315
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- > 35 - < 39.8 other: g/100g
- Temp.:
- 20
- pH:
- 4.2 - 4.4
Any other information on results incl. tables
The solubility (miscibility) of the test item in water at room temperature (23°C) and at 20.0°C ± 0.5°C is >= 35.0 gl100g <39.8 g/100g.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
