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Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Additional information

Justification for classification or non-classification

The registered UVCB substance Reaction products of Reaction products of 3-methylbutanal and 3-methylbut-3-en-1-ol, distillation overheads, acid-treated, hydrogenated contains different constituents which were classified for skin irritation, serious eye damage or eye irritation and respiratory irritation according to Directive 67/548/EEC and Regulation (EC) No 1272/2008as follows:

  • Isovaleraldehyde (0-5%, CAS 590-86-3): irritating to the eye (R 36, Eye Cat 2A) and irritating to the respiratory tract (R37, STOT SE Cat 3)
  • 3-methyl-1-butanol (0-20%, CAS 123-51-3): %): irritating to the eye (R 36, Eye Cat 2A) and irritating to the skin (R38, Skin Cat 2)
  • 3-Buten-1-ol, 3-methyl- (0-5%, CAS 763-32-6): “risk of serious damage to the eyes” (R41) and “irreversible effects on the eye” (Eye Cat 1)
  • 2H-Pyran, tetrahydro-4-methyl-2-(2-methylpropyl)-(30-80%, CAS 13477-62-8): irritating to the skin (R38, Skin Cat 2)
  • Rose oxide (EC 939-429-1, used as read across for DHP1 0-20%, DHP2 5-30% and DHP3 10-50%): irritating to the eye (R 36, Eye Cat 2A) and irritating to the skin (R38, Skin Cat 2)
  • 2H-Pyran-4-ol, tetrahydro-4-methyl-2-(2-methylpropyl)- (10-60%, CAS 63500-71-0): irritating to the eye (R 36, Eye Cat 2A)

 Therefore, a classification

  • with R36/37/38 according to Directive 1999/45/EG
  • and with Skin Irritation Category 2, Eye Irritation Category 2, and STOT SE Category 3 according to Regulation (EC) No 1272/2008
is proposed for the registered UVCB substance Reaction products of 3-methylbutanal and 3-methylbut-3-en-1-ol, distillation overheads, acid-treated, hydrogenated.