Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 424-090-1 | CAS number: 10097-02-6 DMBA
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- other: SNIF Report
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- other: 87/302/EWG, S.118
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes
- Test type:
- other: aerobic
- Total exposure duration:
- 3 h
- Key result
- Duration:
- 3 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 320 mg/L
- Key result
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- 699 mg/L
- Executive summary:
The testing of activated sludge in respiration inhibition test according to OECD 209 guideline under GLP condition show inhibition after 3h of exposure as IC 50= 699 mg/L. The no observed effect concentration after 3 h of exposure was established as NOEC = 320 mg/L.
Reference
Description of key information
Activated Sludge, Respiration Inhibition Test test was performed according toOECD Guideline 209. Inhibitory effects on the respiration of activated sewage sludge after 3 hours of exposure at the test concertation of 100mg/L was not observed. The no observed effect concertation was established as NOEC = 100 mg/L and the IC 50 was established as more than 100 mg/L. The test was performed according to OECD 209 guideline under GLP condition.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 100 mg/L
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
