Registration Dossier
Registration Dossier
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EC number: 456-830-2 | CAS number: 745070-61-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
In-vitro experiments comprised bacterial and mammalian cell genotoxicity as well as the chromosome aberration test. All tests revealed the absence of genotoxicity. Furthermore, an in-vivo micronucleus test that was performed in NMRI mice by gavage administration, gave no evidence of a genotoxic potential of the test substance.
Short description of key information:
In-vitro and in-vivo experiments with the test substance were devoid of a genotoxic result.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
There are conclusive data that classification of the test item with regard to genotoxicity is not necessary.
The test item is not classified for this endpoint in accordance with Directive 67/548/EEC or with the CLP Regulation (EC) No 1272/2008 reflecting GHS regulations.
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