Registration Dossier

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
2000

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: OECD 403 (1981)
GLP compliance:
yes
Limit test:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Product is a waxy, solid material: mass median diameter is not clearly defined.

Test animals

Species:
rat

Administration / exposure

Vehicle:
other: For the product no aerodynamic diameter was used because the substance is a waxy solid.
Duration of exposure:
7 h

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LC50
Effect level:
> 0.005 mg/L air
Exp. duration:
7 h
Mortality:
Male: 0.005 mg/L; Number of animals: 5; Number of deaths: 0
Female: 0.005 mg/L; Number of animals: 5; Number of deaths: 0
Clinical signs:
other: The appearance and the behaviour of the treated animals was not influenced during the 14 days observation period. The body weight was not influenced.
Gross pathology:
No treatment related effects were observed in none of the organs of the animals which were treated with test substance. A decrease of the somatomotoric activities was observed in the control groups and in the test groups as well. This observation was related to the decreased temperature in the exposure chamber.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU